This article showcases our top picks for the best Kentucky based Science And Engineering companies. These startups and companies are taking a variety of approaches to innovating the Science And Engineering industry, but are all exceptional companies well worth a follow.
We tried to pick companies across the size spectrum from cutting edge startups to established brands.
We selected these startups and companies for exceptional performance in one of these categories:
- Innovative ideas
- Innovative route to market
- Innovative product
- Exceptional growth
- Exceptional growth strategy
- Societal impact
Top Kentucky Science And Engineering Companies
Founded in 1980 by Dr. Pearse Lyons, Alltech improves the health and performance of people, animals, and plants through natural nutrition and scientific innovation.
It is a global animal health company providing natural, nutritional supplements for livestock and poultry producers. .
Accent Therapeutics is a biopharmaceutical company developing oncology-focused, small molecule therapies in the emerging field of epitranscriptomics. This field of biology encompasses post-transcriptional chemical modifications of RNA that provide cells with a unique mechanism for regulating proteins critical for cellular growth and differentiation.
By targeting cancer-linked RNA-modifying proteins (RMPs) with precision therapies, they aim to translate extraordinary science into life-changing therapies for patients.. .
University of Louisville
University of Louisville is a public university and a member of the Kentucky state university system. It offers bachelor’s, master’s, and doctorate degrees for students.
University of Louisville offers bachelor’s degrees in 70 fields of study, masters’ degrees in 78, and doctorate degrees in 22. The 2009 annual report of Arizona State University’s Center for Measuring University Performance ranks University of Louisville in the top public research universities in the United States based on its nine measure assessment of total research, federal research, endowment assets, annual giving, national academy members, faculty awards, doctorates granted, postdoctoral appointees, and SAT/ACT range.
The university consists of 12 schools and colleges: College of Arts and Sciences, College of Business, College of Education and Human Development, Graduate School, J. B.
Speed School of Engineering, Kent School of Social Work, Louis D. Brandeis School of Law, School of Dentistry, University of Louisville School of Medicin….
Bexion Pharmaceuticals is developing innovative cures for cancer. Unlike any other potential drug known in development, BXQ-350 has an entirely new and novel mechanism of action.
Studies strongly suggest that specific tumor targeting is the result of targeting Phosphatidylserine patches that are characteristic of tumor cells and neovasculature; and that apoptosis results from activation of acid sphingomyelinase, subsequent generation of ceramide, and elevated levels of caspase.. .
Smart Farm Systems
Smart Farm provides farmers valuable, real-time, actionable information regarding the status of equipment and crops. It has developed a unique, large-area, wireless monitoring, and control system for remotely located irrigation pumps and environmental, soil moisture, and water level monitoring devices.
It also provide newfound monitoring and control for farms and farmers. Its proprietary wireless network provides farmers real-time, actionable information regarding the status of their pump equipment and monitors.
We integrate pump control modules, sensors, and 900-MHz wireless technology into a seamless farm-wide solution. This system enables farmers to provide just the right amount of water at just the right time on a field-by-field basis, resulting in a significant improvement in profitability.
Smart Farm Systems was founded in 2013 and headquartered in Nicholasville, Kentucky.. .
CBA Pharma manufactures, markets, licenses, and distributes drugs for medical oncology community. It offers CBT-1, a pill, which reverses multi-drug resistance in cancer cells and enables the chemotherapy to treat cancer.
The company was formerly known as CBA Pharmaceuticals, Inc. CBA Pharma, Inc.
was incorporated in 1999 and is based in Lexington, Kentucky.. .
Seek Now provide the fast and accurate answers you need for any claim type using the latest in data-driven integrations and tech-forward innovations. Seek Now, previously named Ladder Now, is a disruptive, tech-inspection network offer high quality and reliable inspection services, all while speeding up the carriers claim cycle time and offering exemplary customer service.
Seek Now accelerates the industry trend to virtualize the claim adjustment model with relationships with more than 150 P&C Insurance Carriers in all 50 states. Ladder Now will become a service under the Seek Now brand, along with additional service lines that will expand Seek Now’s growing presence in the industry..
Transposagen Biopharmaceuticals is a privately held biotechnology company that is dedicated to providing unique animal models of human diseases for drug discovery and development. Transposagen is currently focusing on the $1.2 billion/year rodent model market.
The rodent model market is experiencing double-digit annual growth due to the research and development needs of the pharmaceutical industry. It was founded in 2003 and is headquartered in Lexington, Kentucky..
Hummingbird Nano is a commercial company creates the ultra-smooth, circular channel microfluidic chips in a single solid form. Their technology sparks the ability to create new products that can’t be made using the current state of the art methods.
They also make today’s high priced products more affordable, so that they become more commonplace, spur innovation, and give back to society. Hummingbird Nano produces commercial grade products with the speed of injection molding and the flexibility of 3D printing.
The company’s technology is revolutionizing how specific products are manufactured for end-use. Initial applications are focused on small parts such as microfluidic chips and micro-optics..
Medical Search Technologies
The software ingests any type of unstructured text including but not limited to EHR, medical literature, and patient feedback and builds predictive models used for both administrative and clinical functions in healthcare. Use cases include applying CPT and ICD-10 codes to surgical reports, identifying at risk patients for various types of conditions, extracting context from patient feedback including social media that is linked to supplemental data to identify the very small percentage of feedback which needs immediate action, and identifying genetic and disease condition associations.
The model however is flexible and answer any type of questions. The software achieves high model performance by using a proprietary graph database and various algorithms..
TNG Pharmaceuticals, a Louisville, KY based company is focused on the research and development of our patented vaccine, FlyVax. TNG Pharmaceuticals began at the University of Louisville in the Entrepreneurship MBA program.
TNG competed on a global business plan competition circuit: winning four of five competitions, including the world’s largest, richest, and most prestigious competitions.. .
RhinoCyte engages in the development and commercialization of diagnostic tools and therapies for stem cell treatment of multiple degenerative and traumatic neurological diseases. Its technology facilitates functional recovery in patients, including therapeutic stem cell transplantation with cells from the patient’s own nasal cavity eliminating the need for immunosuppressive therapy.
The company’s technology is used to treat conditions, such as Parkinson’s disease, Multiple Sclerosis, Alzheimer’s disease, and spinal cord injuries. RhinoCyte, Inc.
was founded in 2005 and is based in Louisville, Kentucky.. .
MAGNA Pharmaceuticals is a pharmaceutical company that specializes in high-quality pharmaceutical products and optimize the overall health by bringing unique products that are safe and effective, at affordable prices. MAGNA has two product divisions: Consumer (Non-Prescription) and Prescription-Only.
Their consumer products are manufactured to the same high standards as our prescription products. On every product label, on every piece of company stationery, they print MAGNA’s tag line: “Accountability”.
They hold themselves accountable to bring their customers/patients products they can depend upon — to give them results — safely and affordably.. .
MedPro…”Turning Prefilled Upside Down.” In spite of prevention campaigns and safety features, needle stick is still one of the biggest risks for our health care workers. MedPro has developed an integrated safety syringe that is fully passive, deploying safety during normal injection practice.
MedPro offers the best solution to the patient, the healthcare worker and the pharmaceutical company. It can run on existing lines of the pharmaceutical companies.
No new materials come in contact with the drug. And thanks to this device, pharmaceutical companies may actually be able to obtain patent extension for their drugs in the USA..
CTI Science is a biotechnology company engaged in research and development efforts to improve the health of people and animals. The company is developing a flagship product for submission for regulatory drug approval.
It was founded by Dr. Boyd E.
Haley in 2007 and is based in Lexington, Kentucky, United States.. .
Lepidext is engaged in managing the populations of the Lepidoptera pests by introducing bio-pesticides that are species-specific. The company is committed to improving crop security and ensuring agricultural prosperity by combining a deep understanding of insect biology with the skills and experience of farmers.
In 2015, Angelika Fath-Goodin and Bruce Webb established the company in Lexington, Kentucky.. .
Shaip is a leader and innovator in the structured AI Data solutions category. Our strength is in the ability to bridge the gap between industries with AI initiatives and the high-quality data they require.
The ultimate benefit we provide to our clients is the vast amounts of structured data to train their AI models with superior accuracy and the desired outcomes. And it’s all done right the first time to adhere to the most demanding project’s specifications.
We have the people, processes and human-in-the-loop platform to meet these challenging AI projects and we do it within the set timeframes and budgets. This not only enhances an organization’s ability to get ahead in launching their AI products that work as designed, but they can reach their target markets whether they are local, regional, or worldwide.
This is the Shaip difference, where better AI data means better results for you. Shaip has served some of the Fortune 100 clients, such as Google, Microsoft, Amazon, and Samsung; and working with over 10000 collaborators globally..
ApoVax, Inc., a biotechnology company, develops immunotherapies for regulating the immune system to fight against diseases. Its products include ApoVax104, a recombinant protein vaccine that combines with antigens, tumors, and infectious disease markers and stimulates an immune response to create a disease-specific vaccine or therapeutic; and ProtEx, a technology that enables recombinant immunoregulatory proteins to be placed on the surface of cells, tissues, organs, and synthetic surfaces to modulate the immune system.
The company’s products also include ApoVax104-HPV, a therapeutic vaccine for cervical cancer and human papillomavirus infection in women. In addition, its research programs c….
Elwoh Solutions Ag LLC provides local agricultural services and high-quality alfalfa hay available nationwide. The technology division, Elwoh Solutions, provides global technology & engineering services.
Focus on agriculture technology and sustainable agriculture practices is at the forefront.. .
Intrepid Bioinformatics Solutions, Inc. doing business as Div Ted Kalbfleisch, develops web-based database.
It caters to life science researchers. The company was founded in 2006 and is headquartered in Louisville, Kentucky..
Genscape, a DMGT company, is a leading global provider of energy information for commodity and financial markets. Utilizing patented technologies and proprietary algorithms, Genscape provides accurate & timely data on capacities, flow and utilization for all major energy commodities.
The product offerings include real-time information services for power, natural gas and oil in North America and Europe as well as fundamentals-based market intelligence services which market participants rely upon to better understand drivers, risks and dynamics of regional power and gas markets. Genscape is committed to enhancing the market activities of our clients through access to superior fundamental data and market intelligence..
ezDI, Inc. was founded in 2009 with a mission to empower people to deliver innovative solutions that enhance human life.
We focus on developing products that our customers love, products that inspire and provide real and visible value. We empower healthcare professionals across the globe with the ability to organize, store and analyze medical data in real time, and embed the results of the analytics directly into the hospital clinical workflow..
Solidagex, Inc. produces proprietary, natural extracts from the native goldenrod plant for use as bioactive ingredients in the nutrition, cosmetics and Ag-bio industries.
Solidagex has established a scalable supply chain that supports a vertically integrated process for producing its all-natural, green, sustainable products. Our products offer customers the opportunity for multiple benefits from one source of proprietary ingredients.
The multiple high-value properties of Solidagex’s products are attractive to customers in multiple market sectors. The Company’s first commercial supply agreement is with a multi-million dollar company with products in the equine and human nutrition sectors.
Product development agreements are in place with a multi-billion dollar pet food company and an international cosmetics company. Solidagex has generated interest from diverse market sectors.
Examples of these are companies in food packaging, OTC health products, and crop protection.. .
Balluff is a medium-sized company – family-run for four generations, headquartered near Stuttgart, Germany and developed into a leading global player with over 95 years of experience. With a presence in Europe, Asia, North and South America and many other important markets, Balluff now has over 60 locations and 9 production sites, providing global support for their customers in all areas of automation.
Balluff’s North American headquarters has been located in Florence, Kentucky since 1983. Balluff Inc.’s Florence campus includes a new state-of-the-art Customer Support Center and Supply Chain Management building.
The Florence location specializes in the production and market-leading delivery of linear position sensors. In addition, it is the North American distribution and warehouse center for Balluff.
Over 180 employees and a premier distribution network allows us to support their customers in every area of the country.. .
Rocket Pool has a fully integrated API for registered partners. If you’re an exchange, wallet provider or other Ethereum service, you’ll be able to offer staking services for your users easily using our 3rd party partner API and network.
Rocket Pool has two very unique tokens. The RPL token is the main protocol token used by Rocket Pool and was featured in their crowdsale.
They also have the RPD token which allows users to withdraw from staking whenever they wish.. .
RDI has developed and patented a technology platform capable of measuring motion, vibration, and displacement not visible to the human eye. We utilize standard video camera technology in conjunction with our methods and processing algorithms to extract meaningful data.
This technology virtually turns every pixel in the camera’s view into a sensor capable of measuring vibration or motion with sub pixel accuracy. The results naturally lend themselves to a visualization of the motion and several unique market segments.
The opportunities are endless as we can measure and quantify anything that a camera can see. RDI is focused on serving 3 major markets: Vital Signs monitoring of infants-adults, Structural Health Monitoring, and Machine Condition Monitoring..
AllTranz is a specialty pharmaceutical company developing a unique set of dermal delivery products utilizing two proprietary technology platforms consisting of prodrug development and microneedle formulations. AllTranz will be a leader in the development of innovative drug design strategies delivered via unique dermal product solutions to treat neurological and a variety of other disorders.
The broad range of offerings includes solutions for pain modulation, appetite stimulation, smoking cessation, substitution treatment for opiate addiction, as well as alcohol abuse, and abuse deterrent formulations for opiates. AllTranz will utilize its unique dermal drug delivery technology to develop its own products for broad market appeal, as well as partner with pharmaceutical companies seeking to leverage the AllTranz technology platform to improve delivery of existing drugs to form new chemical entities thereby extending patent franchises..
A clean-tech renewable energy reactor platform that harnesses genetically engineered bacteria and harvests the DC electricity, hydrogen gas, and water from their metabolism of organics commonly found in farm waste, plant pulps, river water, and sewage. We have working prototypes and are pilot ready! The company intends to (1) sell the reactor platform, (2) sell the consumables, and (3) sell the accessories for the reactor.
Then, the company intends to (4) monetize globally the carbon and renewable energy credits. They also intend to (5) sell certification to third parties for reactor installation, service, and maintenance..
Xanodyne Pharmaceuticals, Inc. operates as an integrated specialty pharmaceutical company that offers developing and commercializing products in women’s healthcare and pain management in the United States.The company was formerly known as Xanodyne Pharmacal, Inc.
and changed the name to Xanodyne Pharmaceuticals, Inc. in February, 2004.
Xanodyne Pharmaceuticals, Inc. was incorporated in 2000 and is based in Newport, Kentucky..
Angstrom Technologies provides solutions for security, fraud deterrence and brand protection as well as process control, track and trace for manufacturing. The company manufactures organic fluorescent pigments, dyes and additives to provide covert inks, varnishes, and coatings.
Its luminescent chemicals can be integrated with their electronic detection systems which have the ability to accurately measure fluorescent intensity as well as discern between chemicals by luminescent properties. They also help US government agencies detect falsified ID documents and improve border security.
The company designs complete systems to protect document producers from counterfeit and provides an automotive parts manufacturers with a custom designed quality assurance system for load bearing strut assemblies in family mini-vans. Angstrom Technologies was founded by Marwan Aladdin and is headquartered in Florence, Kentucky..
REGISTRAT-MAPI, Inc. is a clinical research organization focusing on late phase studies for biopharmaceutical and medical device companies globally.
It offers consulting services in the areas of late phase study design, epidemiology, risk management planning, and regulatory strategy and interactions; and services for the design and conduct of late phase studies, including prospective and retrospective studies. The company also provides services, such as study operational support, risk management and safety, direct-to-patient contact management, ethical and personal data protection, multi-national observational studies, country-specific studies.
REGISTRAT-MAPI, Inc. was formerly known as REGISTRAT, Inc.
The company was incorporated in 1997 and is based in Lexington, Kentucky with additional offices in North America, Europe, and Asia. REGISTRAT-MAPI has locations in Lyon and Paris, France; Frankfurt am Main, Germany; London, United Kingdom; Lexington, Kentucky; and Philadelphia and Berwyn, Pennsylvania.
As of June 15, 2009, REGISTRAT-MAPI, Inc. operates as a subsidiary of MAPI Developpement, SAS..
G3 pharmaceuticals Inc. is a development-stage biopharmaceutical company.
The company was founded by thought leaders in the field of galectin-3 biology, cardiovascular pharmaceutical development, and carbohydrate drug synthesis and manufacturing. The galectin-3 research by our founders has been cited in the scientific literature over 2,000 times – a testimony to the importance of their studies in understanding the role of galectin-3 and the opportunity for treatment.
The team of founders will guide the company in the pursuit of novel pharmaceuticals that inhibit galectin-3 for treatment of serious medical conditions.. .
We are driven to find a better path to learning, one that will create lasting change. At TutorGen, that path begins in research and comes to life in the classroom and workplace.
We bring together evidence-based approaches with technology and an unwavering focus on the learners, educators, developers, and content creators who use our products.. .
Advanced Cancer Therapeutics
Advanced Cancer Therapeutics, LLC engages in the discovery, development, manufacture, and commercialization of cancer therapeutics. It develops a pipeline of anti-cancer products, including MIF, a macrophage migration inhibitory factor; PU27, a synthetic oligonucleotide that is used as an anticancer compound; PFKFB3, a small molecule compound; CK37, a small molecule that inhibits cell proliferation, choline kinase enzymatic activity, and tumor growth; and a vaccine for human papilloma virus, which is caused for cervical cancer.
The company was founded in 2007 and is based in Louisville, Kentucky.. .
PGxL Laboratories, a reference lab for pharmacogenetics testing. The company operates as both a commercial and research laboratory.
By straddling these two very different worlds, it is engaged with the development of personalized medicine at the level of discovery, assay development and clinical testing. Physicians and researchers using PGXL’s services can be sure they’re getting the very best science available.
The broad application of pharmacogenetics to personalized medicine will, we believe, improve patient outcomes and lower healthcare costs. We see no greater cause than helping physicians bring personalized medicine to standard medical practice..
Toshiba America Electronic Components
Made in the USA, Toshiba America Electronic Components (TAEC) aims to turn the world on to its semiconductors, flash-memory storage devices, LCDs, and radio-frequency components. A subsidiary of Toshiba America, which is owned by Japan’s goliath semiconductor maker Toshiba Corporation, TAEC designs and makes the key components for consumer electronics and mobile devices, digital music players, cameras, medical devices, car electronics, and more.
Electron tubes and optoelectronics are also part of its lineup. The company sells to OEMs, original design manufacturers, contract manufacturers, fabless chip makers and distributors around the globe..
Encore Energy is an independent oil and natural gas developer and operator that specializes in horizontal oil and gas projects. The company’s primary objective is to develop certain properties to be acquired in the future by a larger operator or in preparation for the company to make a strategic move onto the public market in the future.
It controls all facets of operations, including but not limited to, lease acquisition, prospect development, engineering, drilling, completion, and production operations. Encore Energy was founded in 2011 and is headquartered in Bowling Green, Kentucky..
In 1997, CentrAlert began with the creation of the world’s first site-wide emergency alert and notification system for the Department of Energy. When CentrAlert founder Jeff Whattam consulted with the Federal Emergency Management Agency (FEMA, now under Homeland Security) and observed emergency operations centers across the United States, he noticed the need for an intelligent, user-friendly technology that could coordinate a variety of communication channels and initiate protective actions during a crisis.
It had to be capable of integrating disparate technologies, handling multiple events simultaneously, providing facility-wide alerts, disseminating targeted messages, and remaining secure and reliable at all times.. .
HRG offers consulting services in civil, surveying, construction management. In civil sector services like site engineering and Construction Engineering, General utility engineering, Storm drainage facilities, Development of subdivision and industrial parks In surveying service it provides Surveys and mapping studies right-of-way and property surveys, Topographic mapping, Subdivision layout, Drainage surveys, Construction layout.
In construction management services like Assistance in bidding and contract negotiation, Project scheduling and monitoring, Cost control and review, Contract Administration.. .
Electronic Design & Research Inc.
EDR Inc. is a small high-tech company.
Since its formation in 1984, the company has introduced a number of milestone inventions and technological break-through manufacturing number of devices and equipment. EDR conceived the neural-cell principle of processing information that led to the construction of the Super-High Resolution EKG, and later the creation of a new branch of science the Neural-Network.
The invention of the Perpetual Pulse-Width counter opened the door for a charge-pump phase detector, coinless radio, n-shape and narrow-band digital filter, ripple-free high-pass filter, and hundreds of other innovations that have made modern-day digital communication and signal processing possible. The advances in power semiconductors encouraged to invest our resources in the development of Solid-State Relays/Switches since 1998.
In 2002, a patent for an intelligent solid-state relay/breaker was filed and now that relay/breaker (p/n EDR82360) controls power in many submarines. During past several years, EDR Inc.
maintained the leadership in high-power, high-speed, and high-voltage Solid-State Relays/Switches, H-bridge drivers, micro-power normally closed SSR, high-voltage high-speed ½ drivers, and many others.. .
Cornerstone Engineering, Inc. (CEI) is an award winning engineering consulting and construction firm serving a multi-state region from offices in Louisville, Lexington, Indianapolis and Cincinnati.
CEI offers a full range of engineering services including analysis and design of structures, assessment and retrofitting of existing structures, structural special inspections, FRP strengthening, construction and project management services among others.. .
Union Spring Pharmaceuticals
Union Springs Pharmaceuticals (USP) is a specialty OTC company that licenses, develops and commercializes innovative OTC products for the consumer and healthcare markets. They specialize in finding unique solutions for unmet consumer and healthcare professional needs.
They provide focused, disciplined management to optimize products and technologies, and we apply industry-recognized scientific methods, clinical trials and testing methodologies to provide safe, effective products to our customers.. .
Mysteria is an artist-run interactive immersive art experience. Local artists create breathtaking multimedia installations that are immersive, mesmerizing, and interactive.
Based on the opportunity for a new kind of experience, MYSTERIA provides a visceral, adventure-like fantasy space for those living or traveling in/around Louisville, Kentucky.. .
Established in 2000, customKYnetics is a research and development company that is focused on development of rehabilitation engineering products. customKYnetics’ products typically utilize neuromuscular electrical stimulation (NMES) intended for use in muscle strengthening or motor reeducation.
Our products are designed for use by individuals undergoing orthopedic rehabilitation or those with neuromotor disorders secondary to spinal cord injury or stroke. customKYnetics’ core competencies include control and delivery of NMES, instrumentation, and embedded systems..