This article showcases our top picks for the best Colorado based Science And Engineering companies. These startups and companies are taking a variety of approaches to innovating the Science And Engineering industry, but are all exceptional companies well worth a follow.
We tried to pick companies across the size spectrum from cutting edge startups to established brands.
We selected these startups and companies for exceptional performance in one of these categories:
- Innovative ideas
- Innovative route to market
- Innovative product
- Exceptional growth
- Exceptional growth strategy
- Societal impact
Top Colorado Science And Engineering Companies
AMP Robotics creates a scalable robotic system that reduces the cost of recycling and enables smart recycling facilities. AMP Robotics’ solution is a combination of computer vision and machine learning with robots that can identify and rapidly pick recyclable materials off a conveyor belt for market and recovery.
AMP Robotics automates the identification, sorting, and processing of material streams to extract value for material recovery facilities (MRFs) that process municipal solid waste, construction and demolition, e-waste, and auto-shredding. The company’s engineering design reduces the cost of capital investment with modular implementation easily dropping into existing facility infrastructure without costly retrofits or interruption to operations.
AMP Robotics was founded on 2015 and is headquartered in Louisville, Colorado.. .
Inscripta is developing the first benchtop platform for scalable digital genome engineering. The company’s advanced CRISPR-based platform, consisting of an instrument, consumables, software, and assays, offers a fully automated workflow that enables massively parallel, trackable editing of single cells at an unprecedented scale.
Inscripta’s goal is to empower scientists whose gene editing research is stifled by current technical and licensing limitations. By providing this unique platform and engaging in collaborative business practices, such as making its MAD7™ CRISPR nuclease-free for research and development purposes, the company enables scientists to realize a new era of biological discovery..
Boom Technology is making supersonic passenger travel into reality by making a supersonic airliner. Boom was founded on the philosophy that they need to overcome the challenges to supersonic passenger flight, not surrender to them.
They’re making a supersonic aircraft affordable for business travel. Their ultimate goal is a routine supersonic flight for everyone.
Boom Supersonic is redefining what it means to fly in a commercial aircraft by building Overture, its Mach-2.2. It was founded in 2014 and is based in Englewood, Colorado..
SomaLogic operates as a protein biomarker discovery and clinical diagnostics company. It offers SOMAmers (Slow-Offrate Modified Aptamers), which are modified nucleic acid-based protein-binding reagents that are specific for their cognate protein; and SOMAscan that provides protein detection and equipment.
The company’s SOMAmer/SOMAscan technology enables to discover protein biomarker signatures; drug discovery and development; and clinical diagnostics. Its products have applications in the diagnostics of various diseases in oncology, neurology, cardiovascular and metabolic disease, and other diseases and conditions.
SomaLogic was founded in 1999 and is headquartered in Boulder, Colorado.. .
Solid Power is an industry-leading developer of the next-generation of all solid-state rechargeable batteries. Possessing no volatile or flammable liquid components, our solid-state batteries are extremely energy dense while also possessing ultimate safety and reliability.
Together, these performance attributes can enable profound performance improvements of battery-powered devices such as portable electronics, electric vehicles, aircraft and satellites through increased run time, increased safety and lower cost.. .
Outrider, the pioneer in autonomous yard operations for logistics hubs, helps large enterprises improve safety and increase efficiency. The only company exclusively focused on automating all aspects of yard operations, Outrider eliminates manual tasks that are hazardous and repetitive.
Outrider’s mission is to drive the rapid adoption of sustainable freight transportation by deploying zero-emission systems. Outrider is a private company backed by NEA, 8VC, Koch Disruptive Technologies, and other top-tier investors.
For more information, visit www.outrider.ai. .
MycoTechnology utilizes fungi-based food-processing platforms to transform the flavor and value of agricultural products. The platform can be used to solve a variety of challenges faced by the food, beverage, and flavor industries.
MycoTechnology has released ClearTaste, an all-natural, GMO-free, organic bitter blocker that is Kosher and Halal certified. ClearTaste improves the flavor of various agricultural products.
MycoTechnology also engages in fermenting agricultural products with strains of gourmet fungi. The company offers myceliated chocolate as well as robusta and arabica coffee beans.
It develops and licenses technology to the industry to naturally improve the flavor of robusta and arabica coffee. The company was incorporated in 2013 and is based in Aurora, Colorado..
Tortuga AgTech empowers growers by using robots that performs a variety of labor-intensive tasks on the farm, with an emphasis on harvest.Tortuga AgTech’s mission is to build a healthier society, and a thriving ecosystem, through smarter farming. To do this, They want to enable growers to sell better produce – unique, tasty, nutritious food.
They’re doing this by building Digital Horticulture systems, made up of powerful technology like robotics, automation, and precision data analytics and machine learning. These systems will enable advanced growing methods to compete with scale agriculture, which means growers will be able to grow better produce that’s also better for the planet.
The automation of picking, packing, and trimming will reduce significantly the manual labor hours needed to grow to produce. It will also increase yields through denser layouts and optimized grow conditions.
And, they’ll help create full-time local technical jobs as well. And they do all of that while providing fresher, healthier, and more sustainable products to the humans living near their grower customers’ operations..
Sphero bridges the gap between the real world and the virtual world with its smartphone-controlled robots. It began the connected play revolution in 2010 by creating something unlike anything and they never stopped.
They fuse robotic and digital technology into immersive entertainment experiences that ignite imagination and defy expectations. Optimized by data and powered by fun, these ever-evolving experiences are changing the way the world thinks about play..
Ursa Major Technologies
Ursa Major Technologies develops innovative propulsion solutions for the emerging microsatellite and nanosatellite launch market. Its advanced manufacturing optimizes unique part creation.
These engines are greater than 80% additively manufactured by mass using cutting-edge, internally-developed materials and processes. The company was founded in 2015 and is based in Berthoud, Colorado..
Lightning eMotors, formerly Lightning Systems, is at the forefront of fleet electrification, powering familiar commercial vehicle platforms with its electric powertrains. Lightning eMotors produces electric fleet medium- and heavy-duty vehicles, including delivery trucks, shuttle buses, passenger vans, chassis-cab models, and city transit buses.
The Lightning products include elegantly integrated all-electric powertrains for the Ford Transit 350HD passenger and cargo vans, Ford E-450 shuttle bus and cutaway models, Ford F-59 step/food van, Ford F-550 cargo trucks and buses, Chevrolet 6500XD Low Cab Forward model, and 30-foot, 35-foot, and 40-foot transit buses. Founded in 2008, Lightning eMotors is headquartered in Loveland, Colorado..
ArcherDX is advancing molecular pathology with a robust technology platform for genetic mutation detection by next-generation sequencing. By combining proprietary Anchored Multiplexed PCR (AMP™) chemistry in an easy-to-use, lyophilized format and powerful bioinformatics software, the Archer® platform dramatically enhances genetic mutation identification and discovery.
ArcherDX provides oncology-focused research products and is pursuing regulatory approval for multiple companion diagnostic assays.. .
Voyager Space Holdings
Voyager Space Holding is an aviation and aerospace company that specializes in the space exploration industry. The company is driven by its mission is to create a vertically integrated publicly traded NewSpace company capable of delivering any mission humans can conceive.
Voyager Space Holding was founded in 2019 and headquartered in Denver, Colorado.. .
Biodesix is a molecular diagnostics company advancing the development of innovative products for personalizing medicine. The company provides physicians with diagnostic tests for earlier disease detection, more accurate diagnosis, disease monitoring and better therapeutic guidance, which may lead to improved patient outcomes.
Biodesix discovers, develops and commercializes multivariate protein diagnostics based on their proprietary mass spectrometry-based discovery platform. VeriStrat, a multivariate serum protein test, is Biodesix’ first product developed with this technology.
The commercially available test provides oncologists with information to help them select between erlotinib and single-agent chemotherapy for advanced lung cancer patients. Tests are processed in Biodesix’ CLIA-certified laboratory and results are reported in less than 72 hours.
In addition to developing novel diagnostics independently, the company also partners with biotechnology and pharmaceutical companies to develop companion diagnostics to improve utility of therapeutic agents.. .
United Launch Alliance
United Launch Alliance provides spacecraft launch services to the Government of the United States. It is a joint venture of [The Boeing Company](http://www.crunchbase.com/organization/the-boeing-company) and Lockheed Martin Corporation.
It was founded in 2005 and is based in Littleton, Colorado.. .
We are empowering the next wave of intelligent experiences. Think Duolingo + SquareSpace for AI.
swivlStudio provides a toolset for companies to simplify the process of AI training. Our interface allows companies to train their current workforce to provide value in an increasingly AI-first world through step by step guided data labeling exercises.
The employees can then manage the feedback loop to train, test, and tune custom machine learning models that personalize their customers’ experiences via natural language processing, personalized search results, and generalized data categorization. By combining the best of human and machine intelligence, companies can now increase speed to launch and improve accuracy over time..
Unsupervised is an AI-based that finds hidden insights in complex data. It built the first AI-based on unsupervised learning that automatically discovers the most important patterns in data without requiring human guidance or supervision.
It was founded in 2017 and is headquartered in Boulder, Colorado.. .
Sana is the first device that is able to treat all the major compounding co-morbidities of chronic pain – Pain, anxiety, depression and sleep issues. We have great pilot data in Opioid Use Disorder and Fibromyalgia, and have 2 x 120 person RCTs in progress; Duke for Fibromyalgia and Mount Sinai for Neuropathic pain.
Founder developed to solve his own underlying nerve damage pain following a jeep crash in the Yemen, the device uses audio-visual neuromodulation to normalize EEG patterns in the brain, restoring hemispheric balance, and allowing a deep relaxation effect, pain relief and an increase in neuroplasticity. The first prototype fixed founder’s pain for life, and now we are on market as a wellness device under a 513g FDA approval and in pivotal FDA trials for a Denovo for Fibromyalgia, and 510k for Neuropathic pain The device is worn in a reclined position for 16 minutes per session and guides the user into a state of deep relaxation or sleep.
Clinical efficacy was shown in Pain, Anxiety, Depression and Sleep.. .
MiRagen is a biopharmaceutical company that discovers and develops innovative microRNA-targeting therapies to improve human health, specifically in disease areas of high unmet medical need. The company leverages in-house expertise in miRNA biology, oligonucleotide chemistry, and drug development to evaluate and advance best-in-class technologies and high-potential drug candidates for its own pipeline or in conjunction with strategic partners.
The company was founded in 2007 and headquartered in Boulder, Colorado.. .
Mile High Labs
Mile High Labs is an end-to-end GMP certified manufacturer of premium CBD crude oil, distillate, and isolate. Led by a science-based team, Mile High Labs offers extraction, refining, and co-packing services to cultivators, manufacturers, retailers, and companies throughout the consumer packaged goods industry.
The company’s scientifically advanced proprietary process produces the purest CBD Isolate available while supplying a considerable portion of the world’s overall market. Trusted brands choose Mile High Labs for its regulatory expertise, innovative extraction technology and purity-certified CBD.
Mile High Labs extracts exclusively from industrial hemp flower material. Mile High Labs was founded on 2016 and is headquartered in Boulder, Colorado..
Misty Robotics, a spinoff of Sphero, is a hardware company that builds personal robots for homes and offices. Based in Boulder, Colorado, Misty Robotics is building the robot for everyone.
Misty Robotics’ vision is to put personal robots in every home and office. These robots will be seen and treated as our friends, our teammates, and a part of our families — performing helpful tasks, providing safety, and interacting with humans in entertaining and friendly ways that have only been seen before in science fiction..
CH2M Hill is a global engineering services company that offers a diverse range of environmental and engineering consulting services in the U.S. and internationally.
The company provides consulting, design, construction, and operations services for corporations and federal, state, and local governments. CH2M Hill is based in Englewood, Colorado..
Josh is a voice controlled home automation system. Like Siri or Google Now, the Josh programming language is built to support natural language voice commands.
This includes greetings, questions, instructions, and more. Further, Josh is built to control and connect any “smart” device, from any device.
For example, with Josh you can turn on your speakers from your watch, change the temperature from your phone, shut off the lights from your desktop, etc. Initially, Josh will be focused on the smart home, but over time they envision a more general-purpose AI.
Josh will go where you go, making your life easier and more productive.. .
ANDE is dedicated to the development and commercialization of Rapid DNA products for human forensic identification, biothreat detection, and clinical diagnostics. The company believes that moving DNA analysis from the laboratory to the field will dramatically improve societal safety and health.
By reducing crime, exonerating the innocent, monitoring borders, and reuniting families, Rapid DNA represents a fundamental opportunity for the public and private sectors to protect the innocent.. .
CaliberMind is a B2B Customer Data Platform that powers Revenue Marketers at mParticle, Fidelis Cybersecurity, Datavail and other mid-market enterprises, with the data, business intelligence, and automation they need to grow revenue faster, together with sales. The platform lets marketing and ops teams answer simple business questions and automate manual workflows with 1-click: Which marketing programs generate the most revenue? How is my marketing campaign performing? How fast are we driving revenue through the pipeline? How’s our close rate trending over time? Unlike CRM reporting and expensive, general BI tools that take months to implement, run on bad/ partial data and require data analytics skills, CaliberMind can be implemented in one hour by marketing and ops managers.
The platform has 10x faster time-to-insights at 10% of the cost of traditional IT/ BI solutions.. .
Vita Inclinata Technologies
The advent of rotary-wing hoisting systems granted warfighters the ability to conduct rapid insertion and recovery missions, most notably through helicopter Search and Rescue (SAR), MEDEVAC, and Survival, Evasion, Resistance and Escape (SERE) missions. While the addition of hoisting systems on-board rotary-wing aircraft 74 years ago has offered rescue capability, one mission critical attribute of the capability has been fatally flawed all this time: the stabilization of the suspended hoist cable and load.
Vita Inclinata Technologies (Vita) has developed a platform agnostic, autonomous hoist cable control platform: The Load Stability System (LSS), capable of controlling complete oscillatory and rotational motion of a suspended load.. .
North Star Holdings, Inc.
North Star Holdings is a rapidly growing U.S.-based, vertically integrated, multi-state, enterprise-level cannabis operator in states where medical and/or adult-use cannabis is legal. We operate a number of medical and adult-use dispensaries throughout Colorado, own thousands of feet of cultivation and manufacturing facilities that produce cannabis flower, concentrate, and oils that serve our patients and customers.
North Star Holdings Medical & Adult-Use Stores are in prime locations throughout Colorado and have cultivation facilities that are being developed in Las Vegas, Nevada and California. The facilities are well positioned, and they match the ideal picture of a community cannabis dispensary.
North Star Holdings Medical & Adult-Use Stores will ensure that all our customers are given first class treatment whenever they visit our dispensary. Our vision is to become the gold standard for excellence in quality, hygiene, safety, effectiveness, retailing, and professionalism in the delivery of cannabis products and services in the U.S.
markets. The future goals of the Company are to build and operate over a million square feet of cannabis cultivation canopy, operate extraction facilities that produce thousands of kiloliters of the best cannabis oils and extracts, and deliver legendary service to millions of cannabis consumers through dozens of dispensary facilities nationwide.
As adult-use of cannabis becomes legalized in more states, we believe our first-mover advantage in the Medical cannabis markets will give us a competitive advantage over competitors just entering the market. We intend to control as much of the supply chain as possible on a national scale, while also expanding investment in new cannabis technologies and products.
We plan to leverage our management’s experience in operations and first mover advantage to create enduring brands and intellectual property that will have sustainable brand value as the market matures and becomes increasingly competitive. Our goal is to align ourselves with investors and partners who share our core values.
PanTheryx is a U.S. medical nutrition company focused on the research, development, and commercialization of products that promote intestinal health.
The company is engaged in the discovery and development of its proprietary technology platform, advancing clinical testing, and the commercialization of its products that both address the specific dietary needs of children with infectious diarrhea, and support overall intestinal health. The company’s medical nutrition products are regulated in three FDA categories: medical foods, food for special dietary use, and dietary supplements.
PanTheryx was founded in 2007 by Mark A. Braman and is based in Boulder, Colorado..
Reven Pharmaceuticals is a clinical-stage company providing solutions for the treatment of vascular and metabolic-related conditions. Its services offer products such as critical limb ischemia, peripheral arterial disease, coronary artery disease, and endothelial dysfunction that enable patients to get advanced products for their diseases and recover faster.
It was founded in 1999 and headquartered in Golden, Colorado.. .
Infinite Power Solutions
Infinite Power Solutions, Inc. (IPS), a U.S.
based clean-technology company, is the global leader in developing, marketing and manufacturing solid-state, rechargeable thin-film micro-energy storage devices for a variety of micro-electronic applications. Founded in 2001, IPS is privately held with corporate headquarters and manufacturing facilities in the western suburbs of [Denver, CO](http://www.crunchbase.com/maps/search?range=10&geo=denver,+co).
The company has completed the build-out of the world’s first volume manufacturing facility dedicated to the production of its revolutionary thin-film micro-energy cell (MEC(TM)) products (often referred to as thin-film batteries). IPS has recently commenced pre-production activities at this state-of-the-art facility to address growing demand among customers in the wireless sensor, active RFID, powered smart card, medical device, consumer electronics, automotive and civil/military/aerospace markets.
NUBURU is disrupting the world’s battery manufacturing, cell phone manufacturing, and e-mobility markets by providing the best in class technology for welding copper, aluminum and dissimilar metals. The disruptive performance of NUBURU’s lasers has been validated by customers worldwide.
It has invested in automated manufacturing in anticipation of the large demand from these rapidly growing market segments. NUBURU is currently in fund raising mode, seeking mezzanine funding for expanding manufacturing, sales, and marketing and operation organizations.
The company blue laser technology breaks new ground—available as either a standard AO laser or high-brightness MISAKI laser by enabling radical gains in speed and quality in existing metal processes, as well as also unlocking a path to new designs for both conventional laser-metal machining and additive manufacturing (3D printing).. .
Heska is dedicated to perfecting and supporting the core technology and services that truly impact the quality of pet care and help to ensure positive outcomes for veterinarians and their patients. Heska was created by veterinary professionals for veterinary professionals.
Our pledge to customers is to stand behind sound science, following best medical practices even when it’s easier to follow the crowd. After all, once you get through all the claims and the fine print, what’s really important is the accuracy of a diagnosis and the efficacy of a treatment..
Accera is a biotechnology company that engages in the discovery and development of therapeutic drugs for neurodegenerative diseases. It offers Ketasyn, a molecule for Alzheimer’s, Parkinson’s, and age-associated memory impairment.
It was founded in 2001 and is headquartered in Broomfield, Colorado.. .
In 2012, Brody decided to renew the pursuit of his original vision of transforming flight for the commercial marketplace, ultimately bringing a family of vertical takeoff airplanes to market. This led him to form XTI Aircraft Company and design the TriFan 600 as the world’s first vertical takeoff airplane.
With its eXtended Technology and Innovation, XTI is founded on a culture of customer-focused problem solving to meet the evolving needs of modern travelers and promises to change flight and personal freedom and mobility by air travel forever.. .
Bond Pet Foods
Bond Pet Foods makes pet food from real animal protein, without the animal by working with biotechnology. Bond Pet Foods develops meat proteins obtained from animal cells (no slaughter required) and natural microbes.
It is fed a nutrient-rich broth of vitamins, sugars, and minerals in fermentation tanks, without the pharmaceuticals. Bond Pet Foods was founded on 2015 and is headquartered in Boulder, Colorado..
Manatee is a health care company. Manatee empowers providers and families raising children with behavioral or developmental disorders by democratizing mental health care and streamlining communication.
They use digital tools, AI and cognitive behavioral therapy (CBT) methods to gamify treatment and track progress.. .
Woodward is an independent designer, manufacturer, and service provider of control solutions for the aerospace and industrial markets. Their aerospace systems and components optimize the performance of fixed-wing and rotorcraft platforms in commercial, business and military aircraft, ground vehicles, and other equipment.
Their industrial related systems and components enhance the performance of industrial gas and steam turbines, reciprocating engines, compressors, wind turbines, electrical grids, and other energy-related industrial equipment. The company’s innovative fluid energy, combustion control, electrical energy, and motion control systems help customers offer cleaner, more reliable, and more efficient equipment.
Their customers include leading original equipment manufacturers and end-users of their products.. .
Bitsbox is a provider of a monthly subscription box used to offer increasingly advanced projects that teach children to code. The company’s subscription box provides monthly coding projects that teach gradeschoolers how to program application through a website, that runs on phones and tablets, enabling children to learn to code in a hassle free way.
It teaches real coding with crazy fun projects that come in the mail every month. Bitsbox was established in 2014 and is headquartered in Boulder, Colorado..
PharmaJet is a user-friendly, inexpensive device for fluid injection into the body without a needle. Able to compete with traditional needle-syringe delivery, which inherently poses costly needle-stick, re-use, and pass-along disease risk, the technology creates a positive ROI back for every injection.
Unique in the field of jet injection because of its ability to reach all target tissues (IM, SC–0.5 mL, and ID–0.1 mL) accurately and comfortably, supported by wide regulatory claims (global and country-specific) PharmaJet’s platforms are the only commercially available devices that effectively address the 3 B annual immunization market. It was founded in 2005 and headquartered in Golden, Colorado..
Previously known as PneumatiCoat Technologies. Forge Nano is a global leader in surface engineering and precision nano-coating technology.
Forge Nano’s proprietary technology and manufacturing processes make angstrom-thick coatings fast, affordable and commercially viable for a wide range of materials, applications and industries including Lithium Ion batteries, powders, flats and objects.. .
Rezolute is a clinical stage biopharmaceutical company specializing in the development of innovative drug therapies to improve the lives of patients with metabolic and orphan diseases. Rezolute is advancing a diversified portfolio including: RZ358 (Phase 2), an antibody for the ultra-orphan indication of Congenital HyperInsulinism (CHI), with an abbreviated path-to-market strategy; AB101 (Phase 1), a once-weekly injectable basal insulin with the potential to transform the treatment landscape in diabetes management by reducing the therapeutic burden for patients and improving compliance; and a Plasma Kallikrein Inhibitor (PKI) portfolio with two lead compounds, RZ402 targeting Diabetic Macular Edema (DME) and RZ602 targeting Hereditary Angioedema (HAE), an orphan indication.
We believe that our development strategy increases the probability of technical success while reducing safety and efficacy concerns, approval risks, and overall development costs. We also believe that our approach will result in significantly improved and more efficacious therapies with substantial benefits to the global diabetic population..
Left Hand Robotics
Left Hand Robotics has developed the first commercial-class, self-driving snow clearing robot capable of removing snow from sidewalks and walkways. The SnowBot Pro is controlled and monitored remotely from an online management dashboard and uses GPS to follow a pre-programmed path.
Its rotating brush clears a sidewalk from edge-to-edge in a single pass to meet even the highest standards.. .
Bye Aerospace designs, builds, and markets electric-powered and solar-powered aircraft. It offers medium and high altitude unmanned aerial vehicles (UAVs).
George E. Bye founded Bye Aerospace in 2007.
It has its headquarters in Englewood in Colorado.. .
Edison Interactive is a leading software provider that builds customized interactive customer experience solutions for complex environments. Edison has built unparalleled customer experience solutions for industry-leading Fortune 500 companies.
Shark Experience presented by Verizon is now available in 23,000+ golf cars in the U.S., and the Avis Budget Group (ABG) Travel Assistant is available to car rental customers at top airport and local-market locations throughout the U.S. and Canada with plans to expand globally.
With robust analytics and ancillary revenue opportunities, Edison has enabled brands to connect with customers in more relevant and meaningful way.. .
Agribotix is a drone-enabled software company that provides advanced imaging and analysis for precision agriculture. It offers Agribotix Hornet Drone, a rugged low-cost drone airframe purpose-built for operational use on the farm; and Agribotix Infrared and Thermal Sensors, which are thermal cameras that collect images over fields of interest.
It also offers Agribotix Image Processing Services, a software solution that delivers easily viewable georeferenced aerial images.. .
Theralink Technologies is a molecular company specializing in patented, biomarker assay services that target multiple areas of oncology. Their research indicates that genomic and transcriptomic information alone provides an incomplete information resource for physicians to make patient-specific treatment decisions.
The company was founded in 2005 and is headquartered in Baton Rouge, Louisiana.. .
Array BioPharma is a biopharmaceutical company that focuses on the development and commercialization of small molecule drugs to treat patients afflicted with cancer and other high-burden diseases. The company partnered drugs are binimetinib (MEK162), encorafenib (LGX818), selumetinib (partnered with AstraZeneca), danoprevir (partnered with Roche), ipatasertib (partnered with Genentech), larotrectinib (partnered with Loxo Oncology), and tucatinib (partnered with Cascadian Therapeutics).
The company is committed to providing therapies to patients. Array BioPharma was founded on 1998 and is headquartered in Boulder, Colorado..
FourPoint Energy is a private exploration and production company founded by the leadership team of Cordillera Energy Partners following the sale to Apache Corporation in 2012. FourPoint is headquartered in Denver, Colorado with three field offices located throughout Western Oklahoma and the Texas Panhandle.
With over 30 years of industry leading experience, the team at FourPoint is dedicated to creating value that makes a difference. FourPoint has fostered a culture of a dedicated and technically advanced team of professionals who are hard-working and committed to excellence..
Modular Robotics makes robot construction kits made of modular magnetic blocks that can be assembled to create small self-powered robots. They combine sensors, logic, and actuator blocks that young kids can create simple reconfigurable robots that exhibit surprisingly complex behavior.
Cubelets are 40mm plastic cubes with magnetic connectors, just pick them up and start building. MOSS connects using steel spheres and lets kids make robots that slither, drive, and glow.
It was founded in 2008 and is based in Boulder, Colorado.. .
Rebound Technology is rethinking refrigeration through tailored, thermally-driven heat pump architectures that provide efficient, practical, and cost-effective global solutions. Its tailored development approach enables dramatic improvement over the one-size-fits-all, state-of-the-art by utilizing renewable resources, waste heat capture, energy storage, and simple, low-cost construction.
Rebound is currently developing two unique and potentially transformative technologies. IcePoint is a refrigeration cycle with embedded thermal energy storage, designed to save supermarkets 60% on their low-temperature cooling costs.
SunChill is an ultra-low-temperature thermal cycle, designed for developing world agricultural applications, to convert 50C solar thermal energy into 10C refrigeration using locally sourced materials. Each technology represents a departure from the one-size-fits-all energy approach of the 20th century and instead focuses on tailored technologies that solve smaller problems better.
This path reduces the cost of renewable/efficient systems by at an order of magnitude while at the same time growing self-sustaining businesses that create jobs without reliance on government incentives. It is currently funded by US Federal Government research grants..
ARCA biopharma, Inc. is a Colorado-based biopharmaceutical company developing genetically-targeted therapies for cardiovascular diseases.
ARCA’s principal focus is to develop personalized therapies for the treatment of cardiovascular disease through the use of genetics. The Company’s business focus combines expertise in cardiovascular pathophysiology, molecular genetics and clinical development..
Ampio Pharmaceuticals, Inc. develops innovative proprietary drugs selected from its extensive portfolio with the potential to be safe and effective for improving patient care.
The company’s product pipeline includes new uses for approved drugs and new molecular entities (“NMEs”) for important therapeutic areas, including metabolic disease, eye disease, kidney disease, inflammation, sexual dysfunction and CNS disease. Central to the company’s successful clinical development programs are its strong relationships with clinicians, academic medical centers, regional hospitals and specialized product and service providers.
A phase II clinical development program is underway in addition to sponsored basic, translational and clinical research projects aimed at specific disease mechanisms. The company has built a robust portfolio of issued patents and pending patent applications on its products..
MicroBiome Therapeutics is a biotechnology company that develops medical food and pharmaceutical products. The company focuses on developing evidence-based microbiome modulators, which are designed to alter bacteria populations and their environment in the gastrointestinal tract in specific ways to treat and prevent serious health conditions.
Its product includes NM504, which contains a combination of prebiotic and other naturally occurring ingredients formulated to help diabetic individuals achieve healthy blood glucose levels and manage their body weight. MicroBiome Therapeutics was formerly known as NuMe Health LLC.
The company was founded in 2009 and is based in Broomfield, Colorado.. .
Pipeline is a software company that increases the financial performance of companies by closing the gender equity gap. Pipeline’s proprietary SaaS platform uses artificial intelligence to assess, address, and action against the gender biases costing the U.S.
alone $2 trillion. The company’s platform utilizes artificial intelligence to assess, address, and action against gender biases, enabling companies to deliver improved business outcomes and impact company culture..
Taiga Biotechnologies is a clinical-stage company focused on harnessing the immune system to fight infectious disease and cancer. The company’s Bone Marrow Engraftment Enhancer (BMEE) program is developing a first-line product, TBX-1400, to enhance the engraftment of hematopoietic stem and progenitor cells during an allogeneic hematopoietic stem cell transplant (HSCT).
Taiga Biotechnologies lead Cell-Based Immunotherapy product candidate, TBX-3400, uses a patient’s own immune cells to help fight against cancer and infectious disease. TBX-3400 is an autologous cell product made from peripheral blood mononuclear cells that are treated ex vivo with our fusion protein and then delivered intravenously back to the patient the following day.
They developing technologies to generate red blood cells in the laboratory for clinical applications and products to improve the utility of red blood cell products.. .
DMC Biotechnologies produces bio-based chemicals using fermentation. The company’s technology makes products using lower energy and resources, with applications that contribute to a sustainable economy.
DMC Biotechnologies, Inc. was founded in 2014 by Matt Lipscomb and Mike Lynch and is based in Boulder, Colorado, United States..
ADM Labs was created as a subsidiary of ADM Group to provide a centralized and dedicated business unit for our rapid expansion into the hemp & CBD market. ADM Labs’ specific focus is on extraction, manufacturing/processing and wholesale of extract-based products from industrial hemp, primarily CBD isolate and distillate.
By cultivating and developing strategic relationships, including licensing, consignment and distribution agreements with farms, laboratories and processing facilities, ADM Labs currently boasts a number of partnerships and business ventures with numerous global brands and corporations. These unique relationships have positioned ADM Labs as one of the fastest growing and most innovative wholesale producers in the CBD segment while providing industry partners with lower cost, high quality hemp extracts..
Urban Sky is developing the first-ever reusable ‘micro-sat’ version of a near-space balloon, armed with sensors that collect high-value Earth observation data over entire cities, serving a multi-billion dollar imagery market and making daily and weekly aerial imagery collection a cost-effective reality. Leveraging advances in component miniaturization, first-of-its-kind balloon reusability, and the high vantage point of the stratosphere, the Microballoon drastically reduces the cost of high-resolution remote sensing and weather-related data capture over broad areas, leading to more impactful data over more areas than ever before.
With a new wealth of data from the stratosphere – this completely untapped layer of Earth’s atmosphere – we can fundamentally change the collective human understanding of the surface of our planet and urban centers.. .
Carbon America transforms the carbon capture and sequestration (CCS) industry by lowering costs and rapidly increasing deployment. Carbon America is a carbon capture and sequestration developer.
It is vertically integrated, nimble, and built to scale, with a multi-strategy approach to capture and sequester carbon dioxide faster, cheaper, and smarter than the competition. To achieve this, Carbon America has built a team combining world-class engineers, developers, and financiers into a vertically integrated CCS company..
At Shotzr, our mission is to deliver the right images for every marketing moment. In a world with nearly 10 Billion screens, customer experience and attention are driven through imagery.
Shotzr helps you identify your customer, and then identify with them through contextual imagery that matches your audience targeting. Whether you’re doing Facebook and Instagram campaigns, social media marketing, SEM landing pages, or truly dynamic creative, Shotzr provides you with all the imagery you need for digital marketing..
Bolder Surgical exists to serve healthcare providers by developing precisely designed surgical instruments that allow access to confined and often delicate structures. By addressing this comparatively small market, they are able to meet the specific needs of surgeons and promote the advancement of surgical approaches that reach beyond what traditional instruments have allowed.
The company was founded in 2010 and is headquartered in Boulder, Colorado.. .
Precog is a data analysis platform that helps companies productize their data assets. Precog allows companies to store, integrate, and analyze large volumes of measured data.
Featuring the industry-leading implementation of Quirrel, the “R for big data” statistical language, the Precog platform allows companies to create analytics or predictive models that can be deployed as new products or features inside existing products. Companies use Precog to build analytics and reporting into their applications, to turn existing data assets into new data products that can then be resold, and to build advanced analytical features like recommendations and personalizations.
Precog is the next-generation technology that spawned out of ReportGrid, a 2011 [TechStars](/organization/techstars) company. Founded by veteran technologist and entrepreneur John A.
De Goes, Precog is tackling the big data productization problem head-on through a combination of innovative technology and obsessive attention to usability. Precog is funded by RTP Ventures, Resonant Ventures, David G.
Cohen, and other seasoned angels. Its board of directors includes SendGrid CEO Jim Franklin, and serial entrepreneur Kirill Sheynkman..
Enliven Therapeutics is a precision oncology company developing small molecule therapies to extend and improve patient lives. The company’s discovery process combines clinically validated biological targets and industry-leading chemistry to address the limitations of existing therapies.
This approach allows us to efﬁciently and effectively develop precision oncology therapeutics that enhance overall patient well-being.. .
OnKure is a biotechnology company that commercializes a new cancer therapy based on novel, less toxic kinase inhibitor drugs. The company is engaged in the discovery and development of epigenetic therapies for the treatment of cancer that includes selective inhibitors of histone deacetylases.
In pre-clinical models of both hematological and solid tumor cancers, their lead candidate, OKI-179, significantly and safely reduces the growth rate of tumors when dosed by itself or in combination with other targeted therapies. OnKure advances the HDAC3 selective inhibitor OKI-422 into pre-clinical toxicology studies.
The company’s drug candidates aim to treat patients by targeting malignant cells directly, by working in combination with other small molecule therapies and by priming the tumor microenvironment such that checkpoint inhibition is optimized.. .
Divirod is building a global digital platform to account for all water on Earth. Divirod is deploying a network of proprietary radar sensors that measure water in every possible form and create unique datasets with unprecedented accuracy not available until now.
This data is valuable both locally to the sensor and in aggregate to forecast, create alarms, generate reports, increase accountability and enable sustainable practices. Divirod is currently addressing Operational Risks and Water Management..
Panacea Life Sciences
Panacea Life Sciences, a woman-owned and woman-led company, is dedicated to developing and producing the highest-quality, medically-relevant, legal, THC-free, hemp-derived cannabinoid products for consumers and pets from our 51,000 square foot, state-of-the-art, cGMP, extraction, manufacturing, testing and fulfillment center located in Golden, Colorado. Panacea operates in every segment of the CBD product value chain, from cultivation to finished goods, with stringent testing protocols employed at every stage of the supply chain from seed-to-sale.
Panacea offers a line of THC-free, human and animal CBD products, including fast-acting sublingual tablets, soft gels, gummies, tinctures, cosmetics and other topicals.. .
Neuraptive was founded to commercialize innovative technology from the University of Texas. The company is dedicated to bringing this technology to patients.
It develops novel therapeutics and medical products to address the unmet needs of physicians and patients impacted by peripheral nerve injuries. Its franchise therapeutics product is designed for administration during surgery to improve outcomes for patients impacted by acute nerve injury repairs and reconstructive surgical procedures involving peripheral nerves.
Founded in 2016, Neuraptive Therapeutics is headquartered in Lafayette, Colorado.. .
Skyland Analytics provides data analytics and data management software for process manufacturers in the pharmaceutical, chemical, and food and beverage industries. With deep expertise in manufacturing, IT systems, data analytics, product quality, and manufacturing intellectual property.
Skyland is uniquely positioned to support emerging and global companies seeking to enhance product quality and process analysis and manage external manufacturing partners. The Skyland team has developed multiple software products that meet the precise requirements of pharmaceutical manufacturers and the FDA’s standards for the design, testing, and documentation of software..
Company Six is a developer of a technology that advances the awareness and protection of those who put themselves in harm’s way. The company combines advanced robotic platforms with highly-secure cloud-based technology.
CO6’s mission is to provide tools that fundamentally transform the way first responders operate in dangerous environments. Its products are based on nearly a decade of technology development and are designed to deliver an accessible, yet an advanced robotic solution that provides critical awareness..
CereScan is committed to delivering unmatched accuracy and excellence in functional brain diagnostics and personal attention to each and every patient. They specialize in state of the art functional brain imaging utilizing a proprietary process including the latest generation high-resolution gamma camera, the industry’s leading brain image reconstruction software, specially trained board-certified physicians, and research-based knowledge to provide unparalleled diagnostic medical reports.
It was incorporated in 2008 and is based in Littleton, Colorado.. .
Hyperia is a Hyper Intelligence Augmentation that is situated in a conversation between people to capture a comprehensive record of business communication. It is shaped to promote person-to-person collaboration by providing individuals with perfect memory and instantaneous recall.
The Hyperia solution is a result of combining the decades of experience in enterprise security, speech AI, natural language processing and computer vision. It was founded in 2017 and is headquartered in Denver, Colorado..